Diving into Mechanobiology in IPF: Exploring the Targeting of Tissue Mechanics to Halt Fibrosis Progression
- Examine how altered extracellular matrix stiffness and fibroblast mechanotransduction drive IPF pathogenesis
- Highlight mechanotherapeutic strategies designed to normalize aberrant cellular mechano-signaling and disrupt fibrotic feedback loops
- Discuss translational implications for developing therapies that not only slow disease but restore lung tissue function and improve patient outcomes.