Redefining Cough in IPF: Central Mechanisms, Patient Impact & Therapeutic Opportunity

  • Exploring refractory chronic cough as a distinct clinical burden in IPF and ILDs: what are we missing in current trial designs?
  • Is cough the “itch of the lung”? Drawing translational parallels between chronic cough and other hypersensitization syndromes like atopic dermatitis
  • Mechanistic insights: The role of centrally acting, unscheduled opioid receptor modulators in treating IPF-related cough versus peripherally targeted approaches
  • Clinical considerations in trial design, endpoint selection, and measuring meaningful improvement for patients living with IPF-related chronic cough