As we seek to refine our understanding of IPF pathogenesis and therapeutic response, advanced disease modelling remains a critical challenge. This interactive roundtable discussion allows you to share your thoughts on the current limitations in modelling approaches, strategies for improvement, and the feasibility of global initiatives to enhance research resources.

• Beyond the Bleomycin Model: Discussing alternative models such as patient-derived organoids, AI-driven models, and humanized systems to improve disease predictability
• Tissue Scarcity: Exploring the feasibility of a coordinated effort to collect biopsy samples globally for research, addressing logistical and ethical concerns
• Explanted Lungs in Research: Evaluating the role of lungs from transplant recipients in studying disease progression, and their relevance to early-stage IPF
• Building Predictive Models: Identifying criteria for next-gen models that integrate multi-omics and patient samples to enhance translational relevance.