Targeting Pro-Fibrotic Macrophage Signatures & CCN Biology: Translating Preclinical Insights into a Next-Gen IPF Therapeutic
- Highlighting precision-cut lung slices and airway basal cell bronchosphere assays as predictive tools for translational validation
- Demonstrating modulation of pro-fibrotic macrophage markers in human-derived systems in collaboration with FibroFind and Antiverse
- Exploring the therapeutic rationale behind targeting CCN signaling pathways in the context of previous setbacks and renewed opportunities in IPF