Marilyn Glassberg
Chair, Department of Medicine Medicine Loyola University Chicago Stritch School of Medicine
Seminars
The past year has been transformative for IPF, with new therapies, emerging mechanisms, and evolving patient management strategies reshaping the landscape. This panel will provide a strategic, forward-looking overview of how the field has progressed and what the next 12-18 months may hold. Panellists will discuss the expanding pathophysiology of IPF, emerging classifications of therapies, and implications for patient care, clinical development strategy, and communication with stakeholders.
Key Discussion Points:
- How newly approved therapies and emerging candidates are expected to influence IPF treatment and clinical and research priorities in the next 12–18 months.
- Exploring the practical impact of emerging terminology, anti-fibrotic, anti-inflammatory, de-differentiation, fibrolysis, and how these distinctions may shape patient and clinician preferences
- Approaches for ordering, timing, and combining therapies in a multi-drug era, balancing efficacy, safety, and operational feasibility.
- Identifying opportunities, challenges, and areas for collaboration to ensure trials and programs remain aligned with evolving clinical practice
- Examining how interstitial lung abnormalities detected through screening imaging may represent the earliest stages of fibrotic lung disease and identifying the clinical features that predict progression to clinically significant ILD
- Exploring emerging circulating biomarkers, genetic risk factors, and proteomic signatures associated with disease severity, mortality risk, and likelihood of progression
- Understanding how early identification of high-risk patients could enable earlier therapeutic intervention and more efficient recruitment into ILD clinical trials